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Here we are, just a year after the first news of the coronavirus we now call SARS-CoV-2 and the global pandemic known as COVID-19… and scientists have already developed more than one safe & effective vaccine. How did they do that so quickly? I visited the lab whose work directly led to these first COVID vaccines, so you can learn how basic research connects to life-saving medicine. This is how to make a COVID-19 vaccine.
Coronavirus animation courtesy of: Janet Iwasa, University of Utah, with funding from the NSF, the Coronavirus Structural Task Force and the German Federal Ministery of Research
References:
Wrapp, D. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367, 1260–1263 (2020) doi: 10.1126/science.abb2507
Watanabe, Y., Allen, J. D., Wrapp, D., McLellan, J. S. & Crispin, M. Site-specific glycan analysis of the SARS-CoV-2 spike. Science eabb9983 (2020) doi:10.1126/science.abb9983.
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